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Anti-GluN1/NR1 glutamate receptor (N308/48) – Purified

Price: $319
Catalog #: 75-272
Data Sheet (PDF)
Adult rat hippocampus immunohistochemistry
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Product Info

OVERVIEW

Form: Purified
Produced by in vitro bioreactor culture of hybridoma lines followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody at 1mg/mL.

Volume:
100 ┬ÁL

Concentration:
1 mg/mL

Brand:
NeuroMab

Antibody Type:
Monoclonal

Host Species:
Mouse

Antibody Isotype:
IgG1

Species Reactivity:
Human, Mouse, Rat

Applications:
ICC, IHC, WB

Immunogen:
Fusion protein amino acids 42-361 (extracellular N-terminus) of rat NR1(also known as N-methyl-D-aspartate receptor subunit NR1, NMDAR1, NMD-R1, GRIN1, Glutamate receptor subunit zeta-1 and Glurz1, accession number P35439)
Mouse: 99% identity (319/320 amino acids identical)
Human: 99% identity (317/320 amino acids identical)
<50% identity with other Glutamate receptors

Protein Name(s):
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)

Gene Name(s):
Grin1 Nmdar1

Antibody Registry ID:
Purified: AB_11000180

ANTIBODY VALIDATION AND APPLICATION NOTES
This antibody has been validated using the following assays:
Western Blot:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Immunocytochemistry:
This antibody shows the expected staining pattern when used to stain COS cells over-expressing target.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine/immunofluorescence staining pattern when used to stain brain sections.

Expected Banding Pattern:
105 kDa

QUALITY CONTROL
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

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