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    1. Higher titres against highly conserved mammalian gene products

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Prion Protein Antibody

Price: $245
Catalog #: PRN
Data Sheet (PDF)
Cultured fibroblasts cells transiently transfected with a plasmid containing the prion protein cDNA.
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Product Info

Prion protein is the protein responsible for human Creutzfeldt-Jakob Disease (CJD), and somatic mutations of the prion gene are responsible for Gerstmann-Straussler-Scheinker disease and Fatal Familial Insomnia.  The bovine homolog of the prion protein is responsible for bovine Spongioform Encephalopathy (BSE), also known as “Mad Cow Disease.”  In all cases, the prion protein has two folding states, with one state being the “normal” non-pathological form, and the other state inducing a spongioform encephalopathy.

Species Reactivity: Mouse, Human, Rat

Host: Chicken

Form: Mixture of IgY fraction (10 mg/ml) and affinity-purified antibodies (50 ug/ml)

Storage Temperature: -20°C

Applications: Immunocytochemistry

Antibody Type: Polyclonal

Conjugate Type: none

Storage Instructions: -20°C

Special Shipping Instructions: Room Temperature

Shipping Method: Overnight Priority

Chicken anti-Prion antibodies, 200 ul, 10.0 mg/ml. Recommended Dilutions: 1:1000-1:5000 Immunohistochemistry, 1:2500 Western Blot.